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Regulation
of G-Protein Signaling in C. neoformans |
Previous studies have shown that there are two parallel G-protein
signaling pathways functioning in the pathogenic fungus C.
neoformans.
Our research focuses on regulators of G-protein signaling, such
as Crg1, that modulate G-protein signaling. Our long-term goals
are to understand how C. neoformans cells sense and respond to
signals that coordinate their growth and differentiation, to
reveal the relationships between signaling pathways and pathogenesis,
and to discover novel antifungal targets.
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