SEM of HIV infected cell
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Anti-HIV
Immunotoxins
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Immunotoxin treated cell
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We have conjugated anti-HIV monoclonal antibodies to ricin A-chain
to kill HIV-infected cells. These immunotoxins are the most effective
anti-HIV agents when tested in vitro. They have also been found
effective in mouse and macaque models of HIV infection. This form
of therapy may have a place in "activate and purge"
protocols proposed to eliminate HIV from reservoirs within the
body.
1. Presentation
describing this work.
2. Literature citations
for this work.
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