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James M. Hempe, Ph.D. - Publications
1. Hempe, J.M. & Cousins, R.J. (1989) Effect
of EDTA and zinc methionine complex on zinc absorption by rat
intestine. J. Nutr. 119:1179 1187.
2. Hempe, J.M. & Savage, J.E. (1990) Autoclaved egg white
as a protein source for chick diets low in zinc. Poultry Sci.
69:959-965.
3. O'Dell, B.L., Conley Harrison, J., Browning, J.D., Besch Williford,
C., Hempe, J.M. & Savage, J.E. (1990) Zinc deficiency and
peripheral neuropathy in chicks. Proc. Soc. Exp. Biol. Med. 194:1-4.
4. Cousins, R.J. & Hempe, J.M. (1990) Zinc. In Present Knowledge
in Nutrition - Sixth Edition, pages 251-260. Brown, M.L., ed.
International Life Sciences Institute - Nutrition Foundation,
Washington, D.C.
5. Hempe, J.M. & Cousins, R.J. (1991) Cysteine-rich intestinal
protein binds zinc during transmucosal zinc transport. Proc. Nat.
Acad. Sci. 88:9671-9674.
6. Hempe, J.M., Carlson, J.M. & Cousins, R.J. (1991) Intestinal
metallothionein gene expression and zinc absorption are zinc-responsive
but refractory to dexamethasone and interleukin 1?. J. Nutr. 121:1389-1396.
7. Hempe, J.M. & Cousins, R.J. (1992) Cysteine-rich intestinal
protein and intestinal metallothionein: an inverse relationship
as a conceptual model for zinc absorption in rats. J. Nutr. 122:89-95.
8. Hempe, J.M. & Craver, R.D. (1994) Quantification of hemoglobin
variants by capillary isoelectric focusing. Clin. Chem. 40:2288-2295.
9. Levenson, C.W., Shay, N.F., Hempe, J.M. & Cousins, R.J.
(1994) Expression of cysteine-rich intestinal protein in rat intestine
and transfected cells is not zinc dependent. J. Nutr. 124:13-17.
10. Escobar, O., Sandoval, M., Vargas, A. & Hempe, J.M. (1995)
Role of metallothionein and cysteine-rich intestinal protein in
the regulation of zinc absorption by diabetic rats. Pediatr. Res.
37:321-327.
11. Sandoval, M., Miller, M.J.S., Sadowska-Krowicka, H., Zhang,
X.J. & Hempe, J.M. (1995) Decreased zinc absorption in guinea
pig models of acute and chronic ileitis. J. Nutr. Biochem. 6:534-539.
12. Hempe, J.M., Granger, J.N. & Craver, R.D. (1997) Analysis
of hemoglobin variants by capillary isoelectric focusing. J. Cap.
Elec. 4:131-135.
13. Hempe, J.M., Granger, J.N. & Craver, R.D. (1997) Capillary
isoelectric focusing of hemoglobin variants in the pediatric clinical
laboratory. Electrophoresis 18:1785-1795 (Invited manuscript).
14. Craver, R.D., Abermanis, J.G., Warrier, R.P., Ode, D.L. &
Hempe, J.M. (1997) Hemoglobin A2 levels in normal individuals,
sickle cell disease, sickle cell trait, and ?-thalassemia by capillary
isoelectric focusing. Am. J. Clin. Path. 107:88-91.
15. Vehaskari, V.M., Hempe, J.M., Manning, J., Aviles, D.H. &
Carmichael, M.C. (1998) Developmental regulation of ENaC subunit
mRNA levels in rat kidney. Am. J. Physiol. 274:C1661-C1666.
16. Udall, J.N., Jr., Hempe, J.M., Schmidt-Sommerfeld, E., Scheer,
W.D., Mannick, E., Blecker, U. & Correa, H. (1999) Longitudinal
analysis of plasma cytomegalovirus deoxyribonucleic acid in a
boy with Crohn’s disease and cytomegalovirus gastroenteritis.
Journal of Pediatric Gastroenterology and Nutrition 28:502-505.
17. Yu, Zhongxin, Scheer, W.D. & Hempe, J.M. (1999) Quantification
of human cytomegalovirus by competitive PCR and capillary electrophoresis.
In Methods in Molecular Medicine: Clinical Applications of Capillary
Electrophoresis, pages 65-80. Palfrey, S.M., ed. Humana Press,
Totowa, NJ.
18. Hempe, J.M. & Craver, R.D. (1999) Laboratory diagnosis
of structural hemoglobinopathies and thalassemias by capillary
isoelectric focusing. In Methods in Molecular Medicine: Clinical
Applications of Capillary Electrophoresis, pages 81-98. Palfrey,
S.M., ed. Humana Press, Totowa, NJ.
19. Rodriguez, J., Sandoval, M., O'Leary, J.P. & Hempe, J.M.
(2000) Zinc, copper, and metallothionein metabolism following
jejunoileal bypass surgery or small bowel resection in rats. American
Surgeon 11:1004-1010
20. Barkemeyer, B.M. & Hempe, J.M. (2000) The effect of transfusion
on hemoglobin variants in preterm infants. Journal of Perinatology
20:355-358.
21. Hempe, J.M. & Craver, R.D. (2000) Separation of hemoglobin
variants with similar charge by capillary isoelectric focusing:
Value of isoelectric point for identification of common and uncommon
hemoglobin variants. Electrophoresis 21:743-748 (Invited manuscript).
22. Chalew, S.A., Gomez, R., Butler, A., Hempe, J., Compton, T.,
Mercante, D., Rao, J. & Vargas, A. (2000) Predictors of glycemic
control in children with type 1 diabetes: the importance of race.
Journal of Diabetes and its Complications 14: 71-77.
23. Leiva, L.E., Butler, B., Hempe, J., Ortigas, A.P. & Sorensen,
R.U. (2001) Up-regulation of CD40 ligand and induction of a Th2
response in children immunized with pneumococcal polysaccharide
vaccines. Clinical & Diagnostic Laboratory Immunology 8: 233-240.
24. Hempe, J.M., Vargas, A. & Craver, R.D. (2001) Clinical
analysis of structural hemoglobin variants and HbA1c by capillary
isoelectric focusing. In Pathology and Laboratory Medicine: Clinical
and Forensic Applications of Capillary Electrophoresis, pages
145-164. Petersen, J.R. & Mohammad, A.A., eds. Humana Press,
Totowa, NJ.
25. Begue, R.E., Ukarapol, N., Hempe, J.M., Correa, H., Gomez,
R. & Vargas, A. (2002) Association between Helicobacter felis-induced
gastritis and elevated glycated hemoglobin levels in a mouse model
of type 1 diabetes. Journal of Infectious Diseases 185:1463-1467.
26. Hempe, J.M., Gomez R., McCarter R. & Chalew S.A. (2002)
High and low hemoglobin glycation phenotypes in type 1 diabetes:
a challenge for interpretation of glycemic control. Journal of
Diabetes and its Complications 16:313-320.
27. Goldstein, S.L., Currier, H., Waters, L., Hempe, J.M. &
Silverstein, D.M. (2003) Acute and chronic inflammation in pediatric
patients receiving hemodialysis. Journal of Pediatrics 143:653-657.
28. Somjee, S., Yu, L.C., Hagar, A. & Hempe, J.M. (2004) Diagnosis
and characterization of Hb C/Iowa: a rare but easily misidentified
compound heterozygous condition. Hemoglobin 28:7-13.
29. McCarter R., Hempe, J.M., Gomez R. & Chalew S.A. (2004)
Biological Variation in Glycated Hemoglobin Predicts Risk of Retinopathy
and Nephropathy in Type 1 Diabetes. Diabetes Care 27:1259-64.
30. Somjee, S.S., Warrier, R.P. Thomson, J.L., Ory-Ascani, &
Hempe, J.M. (2005) Advanced Glycation End-Products in Sickle Cell
Anemia. British Journal of Haematology 129:112-118.
31. Chalew S.A., McCarter R., Thomas, J., Thomson, J.L., &
Hempe, J.M. (2005) A Comparison of the Glycosylation Gap and Hemoglobin
Glycation Index in Patients with Diabetes. Journal of Diabetes
and its Complications 19: 218-222.
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